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HDAC7 Antikörper

HDAC7 Reaktivität: Human WB Wirt: Kaninchen Monoclonal 3H7 unconjugated
Produktnummer ABIN5557306
  • Target Alle HDAC7 Antikörper anzeigen
    HDAC7 (Histone Deacetylase 7 (HDAC7))
    Reaktivität
    • 98
    • 66
    • 54
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 107
    • 6
    Kaninchen
    Klonalität
    • 101
    • 12
    Monoklonal
    Konjugat
    • 52
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser HDAC7 Antikörper ist unkonjugiert
    Applikation
    • 74
    • 45
    • 21
    • 15
    • 14
    • 14
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Recombinant human HDAC7 protein, around N-terminal 150aa.
    Klon
    3H7
    Isotyp
    IgG
    Top Product
    Discover our top product HDAC7 Primärantikörper
  • Applikationshinweise
    WB 1:1000-2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C
    Haltbarkeit
    12 months
  • Target
    HDAC7 (Histone Deacetylase 7 (HDAC7))
    Andere Bezeichnung
    HDAC7 (HDAC7 Produkte)
    Hintergrund

    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).

    Synonyms: Histone deacetylase 7, HDAC7

    Gen-ID
    51564
    UniProt
    Q8WUI4
    Pathways
    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
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