HDAC7 Antikörper
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- Target Alle HDAC7 Antikörper anzeigen
- HDAC7 (Histone Deacetylase 7 (HDAC7))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser HDAC7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Recombinant human HDAC7 protein, around N-terminal 150aa.
- Klon
- 3H7
- Isotyp
- IgG
- Top Product
- Discover our top product HDAC7 Primärantikörper
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- Applikationshinweise
- WB 1:1000-2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C
- Haltbarkeit
- 12 months
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- Target
- HDAC7 (Histone Deacetylase 7 (HDAC7))
- Andere Bezeichnung
- HDAC7 (HDAC7 Produkte)
- Hintergrund
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Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).
Synonyms: Histone deacetylase 7, HDAC7
- Gen-ID
- 51564
- UniProt
- Q8WUI4
- Pathways
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
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