HDAC7 Antikörper (N-Term)

Produktnummer ABIN5557306

Der Kaninchen Monoklonal anti-HDAC7 Antikörper wird verwendet zum Nachweis von HDAC7 in Proben von Human. Er wurde validiert für WB, IHC (p), IF, FACS, ICC und IHC (fro).

Kurzübersicht für HDAC7 Antikörper (N-Term) (ABIN5557306)

Target: HDAC7 (Histone Deacetylase 7 (HDAC7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser HDAC7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 3H7

Produktdetails anti-HDAC7 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: HDAC7 Recombinant Antibody

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant human HDAC7 protein, around N-terminal 150aa.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:500-2000), IHC-P(1:50-200), IHC-F(1:50-200), IF(1:50-200), Flow-Cyt(1:50-200), ICC/IF(1:50-100)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu HDAC7

Target: HDAC7 (Histone Deacetylase 7 (HDAC7))

Andere Bezeichnung: HDAC7

Hintergrund:

Synonyms: Histone deacetylase 7, HDAC7

Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).

Gen-ID: 51564

UniProt: Q8WUI4

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development