CCR6 Antikörper

Produktnummer ABIN121968

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-CCR6 Antikörper (ABIN121968) detektiert spezifisch CCR6 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CCR6 Antikörper (ABIN121968)

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CCR6 Antikörper

Spezifität: Reacts with C-C Chemokine Receptor 6 (Family: GPCR, Subfamily: Chemokine).

Aufreinigung: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin embedded sections: 2-9 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Referenzen für anti-CCR6 Antikörper (ABIN121968)

Dorgham, Dejou, Piesse, Gorochov, Pène, Yssel: "Identification of the Single Immunodominant Region of the Native Human CC Chemokine Receptor 6 Recognized by Mouse Monoclonal Antibodies." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157740, (2017) (PubMed).

Details zu CCR6

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Andere Bezeichnung: CD196 / CCR6

Hintergrund: CCR6 is a Chemokine Receptor that is activated by MIP3alpha/Larc binding. CCR6 has been shown to be upregulated in psoriatic skin. CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells but not in natural killer cells, monocytes, or granulocytes from spleen, lymph node, appendix, and fetal liver. ESTs have been isolated from liver/spleen, lymph, and fetal lung / testis /B cell libraries.Synonyms: C-C CKR-6, C-C chemokine receptor type 6, CC-CKR-6, CCR-6, CKRL3, CMKBR6, Chemokine receptor-like 3, DRY6, G-protein coupled receptor 29, GPR-CY4, GPR29, LARC receptor, STRL22

Gen-ID: 1235

UniProt: P51684

Pathways: cAMP Metabolic Process