SSH1 Antikörper (AA 1032-1044)
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- Target Alle SSH1 Antikörper anzeigen
- SSH1 (Slingshot Homolog 1 (SSH1))
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Bindungsspezifität
- AA 1032-1044
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SSH1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Immunogen
- Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. coli.
- Klon
- 6C11G9
- Isotyp
- IgG1
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- Applikationshinweise
- ELISA: 1:10000, WB: , IHC: 1:200 - 1:1000, ICC: , FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- SSH1 (Slingshot Homolog 1 (SSH1))
- Andere Bezeichnung
- SLINGSHOT-1L (SSH1 Produkte)
- Synonyme
- AW551225 antikoerper, Gm1394 antikoerper, Gm1395 antikoerper, SSH-1 antikoerper, mSSH-1L antikoerper, SSH1L antikoerper, slingshot homolog 1 (Drosophila) antikoerper, slingshot protein phosphatase 1 antikoerper, Ssh1 antikoerper, SSH1 antikoerper
- Hintergrund
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Description: The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,
Aliases: SSH1,SSH1L
- Molekulargewicht
- 115.5 kDa
- Gen-ID
- 54434
- HGNC
- 54434
- Pathways
- CXCR4-mediated Signaling Events
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