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SSH1 Antikörper (AA 1032-1044)

Der Maus Monoklonal Anti-SSH1-Antikörper wurde für ELISA, IHC und FACS validiert. Er ist geeignet, SSH1 in Proben von Human zu detektieren.
Produktnummer ABIN5542668

Kurzübersicht für SSH1 Antikörper (AA 1032-1044) (ABIN5542668)

Target

Alle SSH1 Antikörper anzeigen
SSH1 (Slingshot Homolog 1 (SSH1))

Reaktivität

  • 39
  • 5
  • 3
  • 3
Human

Wirt

  • 25
  • 14
Maus

Klonalität

  • 26
  • 13
Monoklonal

Konjugat

  • 22
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SSH1 Antikörper ist unkonjugiert

Applikation

  • 27
  • 20
  • 6
  • 5
  • 4
  • 3
  • 3
  • 1
ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon

6C11G9
  • Bindungsspezifität

    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1032-1044

    Verwendungszweck

    SLINGSHOT-1L Antibody

    Aufreinigung

    Purified antibody

    Immunogen

    Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified antibody in PBS with 0.05 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target

    SSH1 (Slingshot Homolog 1 (SSH1))

    Andere Bezeichnung

    SLINGSHOT-1L

    Hintergrund

    The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Molekulargewicht

    115.5 kDa

    Gen-ID

    54434

    UniProt

    Q8WYL5

    Pathways

    CXCR4-mediated Signaling Events
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