SSH1 Antikörper (AA 1032-1044)
Kurzübersicht für SSH1 Antikörper (AA 1032-1044) (ABIN5542668)
Target
Alle SSH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1032-1044
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Verwendungszweck
- SLINGSHOT-1L Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. Coli.
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Isotyp
- IgG1
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anti-Slingshot Homolog 1 (SSH1) (AA 1032-1044) antibody
SSH1 Reaktivität: Human ELISA, FACS, ICC Wirt: Maus Monoclonal 1A5C8 unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 752-849) antibodySSH1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2F9 unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 950-1049) antibodySSH1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1D2 unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 928-1049) antibodySSH1 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 227-254), (N-Term) antibodySSH1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40522 unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 1-1049) antibodySSH1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 1-1049) antibodySSH1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SSH1 (Slingshot Homolog 1 (SSH1))
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Andere Bezeichnung
- SLINGSHOT-1L
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Hintergrund
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The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Molekulargewicht
- 115.5 kDa
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Gen-ID
- 54434
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UniProt
- Q8WYL5
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Pathways
- CXCR4-mediated Signaling Events
Target
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