DNMT3A Antikörper (AA 46-180)
Kurzübersicht für DNMT3A Antikörper (AA 46-180) (ABIN5542516)
Target
Alle DNMT3A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 46-180
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Verwendungszweck
- DNMT3A Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human DNMT3A (AA: 46-180) expressed in E. Coli.
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Isotyp
- IgG2a
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
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Andere Bezeichnung
- DNMT3A
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Hintergrund
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CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molekulargewicht
- 102 kDa
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Gen-ID
- 1788
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UniProt
- Q9Y6K1
Target
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