RAP1GAP Antikörper (AA 412-660)

Produktnummer ABIN5542476

Der Maus Monoklonal Anti-RAP1GAP-Antikörper wurde für ELISA und FACS validiert. Er ist geeignet, RAP1GAP in Proben von Human zu detektieren.

Kurzübersicht für RAP1GAP Antikörper (AA 412-660) (ABIN5542476)

Target: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RAP1GAP Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Klon: 2G7B6

Produktdetails anti-RAP1GAP Antikörper

Bindungsspezifität: AA 412-660

Verwendungszweck: RAP1GAP Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human RAP1GAP (AA: 412-660) expressed in E. Coli.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu RAP1GAP

Target: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Andere Bezeichnung: RAP1GAP

Hintergrund: This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Molekulargewicht: 73.4 kDa

UniProt: P47736