MIB1 Antikörper (AA 6-221)
Kurzübersicht für MIB1 Antikörper (AA 6-221) (ABIN5542433)
Target
Alle MIB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 6-221
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Verwendungszweck
- MIB1 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human MIB1 (AA: 6-221) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
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Andere Bezeichnung
- MIB1
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Hintergrund
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This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
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Molekulargewicht
- 110 kDa
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Gen-ID
- 57534
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UniProt
- Q86YT6
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Pathways
- SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
Target
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