alpha Adducin Antikörper (AA 1-193)

Produktnummer ABIN5542416

Der Maus Monoklonal Anti-alpha Adducin-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, alpha Adducin in Proben von Human zu detektieren.

Kurzübersicht für alpha Adducin Antikörper (AA 1-193) (ABIN5542416)

Target: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser alpha Adducin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Klon: 5D4H1

Produktdetails anti-alpha Adducin Antikörper

Bindungsspezifität: AA 1-193

Verwendungszweck: ADD1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human ADD1 (AA: 1-193) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu alpha Adducin

Target: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Andere Bezeichnung: ADD1

Hintergrund: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.

Molekulargewicht: 81 kDa

Gen-ID: 118

UniProt: P35611

Pathways: Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling