FH Antikörper (AA 44-510)

Produktnummer ABIN5542251

Der Maus Monoklonal Anti-FH-Antikörper wurde für WB und EIA validiert. Er ist geeignet, FH in Proben von Human zu detektieren.

Kurzübersicht für FH Antikörper (AA 44-510) (ABIN5542251)

Target: FH (Fumarate Hydratase (FH))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT3F6

Produktdetails anti-FH Antikörper

Bindungsspezifität: AA 44-510

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human Fumarase (44-510aa) purified from E. coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu FH

Target: FH (Fumarate Hydratase (FH))

Andere Bezeichnung: fumarase

Hintergrund: Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-termil extended mitochondrial form. The N-termil extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor.

UniProt: P07954