GFRA1 Antikörper

Produktnummer ABIN5542200

Der Huhn-Polyklonal Anti-GFRA1-Antikörper wurde für WB, IF, ICC und EIA validiert. Er ist geeignet zum Nachweis von GFRA1 in Proben aus Human. }

Kurzübersicht für GFRA1 Antikörper (ABIN5542200)

Target: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Reaktivität: Human

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser GFRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Enzyme Immunoassay (EIA)

Produktdetails anti-GFRA1 Antikörper

Spezifität: This antibody detects Human GFRa-1 and doesn't cross-react with hGFRa-2, hGFRa-3, hGFRa-4. Other species not tested.

Aufreinigung: Affinity Chromatography

Immunogen: Recombinant His-tagged human GFRa-1 protein produced using CHO-based. For production of hGFRa-1, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant.

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: ELISA: 1/80000-1/160000. Western blot: 1/5000-1/10000. Immunofluorescence: 1/1000-1/2000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Concentrated Ammonium Sulphate in PBS pH 7.4

Lagerung: 4 °C

Informationen zur Lagerung: Upon receipt, store at 2-8°C. As product is (NH4) 2 SO 4 precipitate, mix well by pipetting or vortexing prior use. Shelf life: One year from despatch.

Details zu GFRA1

Target: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Andere Bezeichnung: gfra1,gdnfr-alpha

Hintergrund: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The GFRa-1 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674).

UniProt: P56159