SSR4 Antikörper (AA 24-144)

Produktnummer ABIN5542183

Produktdetails anti-SSR4 Antikörper

Target: SSR4 (Signal Sequence Receptor, delta (SSR4))

Bindungsspezifität: AA 24-144

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SSR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human SSR4 (24-144aa) purified from E. coli

Klon: AT26G5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu SSR4

Target: SSR4 (Signal Sequence Receptor, delta (SSR4))

Andere Bezeichnung: ssr4,trapd (SSR4 Produkte)

Synonyme: TRAPD antikoerper, AW743063 antikoerper, C78062 antikoerper, Trap antikoerper, signal sequence receptor subunit 4 antikoerper, signal sequence receptor, delta antikoerper, SSR4 antikoerper, Ssr4 antikoerper

Hintergrund: SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. SSR4 consists of six exons and is approximately 70 kb telomeric to the ALD gene. Although alternative splicing of exon 5 has not been detected in human SSR4, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus.

UniProt: P51571