PRPS1 Antikörper (AA 1-318)

Produktnummer ABIN5542153

Der Maus Monoklonal anti-PRPS1 Antikörper (Klon AT1E11) (ABIN5542153) detektiert spezifisch PRPS1 in WB, IF, ICC und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PRPS1 Antikörper (AA 1-318) (ABIN5542153)

Target: PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRPS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Enzyme Immunoassay (EIA)

Klon: AT1E11

Produktdetails anti-PRPS1 Antikörper

Bindungsspezifität: AA 1-318

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human PRPS1 (1-318aa) purified from E. coli

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis and Immunofluorescence / Immnunocytochemistry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu PRPS1

Target: PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

Andere Bezeichnung: prps1

Hintergrund: PRPS1 is an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. A mutation in PRPS1 may result in PRPS superactivity, a disease characterized by gout and the overproduction of purine nucleotides, uric acid and PRPP. PRPS1 mutations can also lead to a reduction in PRPS1 activity resulting in ARTS syndrome or CMTX5 (Charcot-Marie-Tooth disease X-linked recessive type 5).

UniProt: P60891

Pathways: Ribonucleoside Biosynthetic Process