PRPS1 Antikörper (AA 1-318)

Produktnummer ABIN5542153

Produktdetails anti-PRPS1 Antikörper

Target: PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

Bindungsspezifität: AA 1-318

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRPS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Immunocytochemistry (ICC)

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human PRPS1 (1-318aa) purified from E. coli

Klon: AT1E11

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis and Immunofluorescence / Immnunocytochemistry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu PRPS1

Target: PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

Andere Bezeichnung: prps1 (PRPS1 Produkte)

Synonyme: ARTS antikoerper, CMTX5 antikoerper, DFN2 antikoerper, DFNX1 antikoerper, PPRibP antikoerper, PRS-I antikoerper, PRSI antikoerper, 2310010D17Rik antikoerper, C76571 antikoerper, C76678 antikoerper, Prps-1 antikoerper, cb96 antikoerper, prps1 antikoerper, wu:fa18f03 antikoerper, wu:fb33h12 antikoerper, wu:fd26g08 antikoerper, zgc:55299 antikoerper, zgc:76932 antikoerper, arts antikoerper, cmtx5 antikoerper, ppribp antikoerper, prsi antikoerper, fc64g03 antikoerper, im:6909503 antikoerper, wu:fc64g03 antikoerper, zgc:153331 antikoerper, phosphoribosyl pyrophosphate synthetase 1 antikoerper, phosphoribosyl pyrophosphate synthetase 1A antikoerper, phosphoribosyl pyrophosphate synthetase 1 L homeolog antikoerper, phosphoribosyl pyrophosphate synthetase 1B antikoerper, PRPS1 antikoerper, Prps1 antikoerper, prps1a antikoerper, prps1.L antikoerper, prps1b antikoerper

Hintergrund: PRPS1 is an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. A mutation in PRPS1 may result in PRPS superactivity, a disease characterized by gout and the overproduction of purine nucleotides, uric acid and PRPP. PRPS1 mutations can also lead to a reduction in PRPS1 activity resulting in ARTS syndrome or CMTX5 (Charcot-Marie-Tooth disease X-linked recessive type 5).

UniProt: P60891

Pathways: Ribonucleoside Biosynthetic Process