MFAP4 Antikörper (AA 22-255)

Produktnummer ABIN5542149

Der Maus Monoklonal Anti-MFAP4-Antikörper wurde für WB und EIA validiert. Er ist geeignet, MFAP4 in Proben von Human zu detektieren.

Kurzübersicht für MFAP4 Antikörper (AA 22-255) (ABIN5542149)

Target: MFAP4 (Microfibrillar-Associated Protein 4 (MFAP4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MFAP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT12D11

Produktdetails anti-MFAP4 Antikörper

Bindungsspezifität: AA 22-255

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human MFAP4 (22-255aa) purified from E. coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu MFAP4

Target: MFAP4 (Microfibrillar-Associated Protein 4 (MFAP4))

Andere Bezeichnung: mfap4

Hintergrund: Several microfibril associated proteins (MFAPs) have been cloned, including MFAP1, MFAP3 and MFAP4. The MFAP1 and MFAP3 genes are localized near the fibrillin genes FBN1 and FBN2, respectively. Mutations in FBN1 are linked to Marfan syndrome. Mutations in FBN2 have been linked to congenital contractural arachnodactyly. This suggests roles for MFAP1 and MFAP3 in heritable diseases affecting microfibrils. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. Also, MFAP4 play an important role in calcium-dependent cell adhesion or intercellular interactions. These structural features of MFAP4 suggest that it is an extracellular matrix protein involved in cell adhesion or intercellular interactions.

UniProt: P55083