SNAIL Antikörper (AA 1-264)

Produktnummer ABIN5542116

Der Maus Monoklonal Anti-SNAIL-Antikörper wurde für WB und EIA validiert. Er ist geeignet, SNAIL in Proben von Human zu detektieren.

Kurzübersicht für SNAIL Antikörper (AA 1-264) (ABIN5542116)

Target: SNAIL (SNAI1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SNAIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT2D5

Produktdetails anti-SNAIL Antikörper

Bindungsspezifität: AA 1-264

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human SNAI1 (1-264aa) purified from E. coli

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.Recommended starting dilution is 1:1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu SNAIL

Target: SNAIL (SNAI1)

Andere Bezeichnung: snai1

Hintergrund: SNAI1, also known as Snail homolog 1, is involved in the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. This protein binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. Both SNAI1 and SLUG belong to the snail C2H2-type zinc-finger protein family. SLUG is a transcriptional repressor, involved in the generation and migration of neural crest cells. SNAI1 is expressed in mesenchymal, epithelial cell lines and highest expression in kidney.

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling