LGR4 Antikörper

Produktnummer ABIN5541955

Dieser Anti-LGR4 Antikörper ist ein Ratte Monoklonal Antikörper zur Detektion von LGR4 in FACS und EIA. Geeignet für Human.

Kurzübersicht für LGR4 Antikörper (ABIN5541955)

Target: LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser LGR4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: BBX-1H1

Produktdetails anti-LGR4 Antikörper

Spezifität: Recognizes Human LGR4 / GPR48. Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.

Kreuzreaktivität (Details): Does not cross react with Mouse.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: cDNA encoding Human LGR4

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 1.2 μg/10 6 cells. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.2

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu LGR4

Target: LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))

Andere Bezeichnung: lgr4,gpr48

Hintergrund: LGR4 (Leucine-rich repeat- containing G protein-coupled receptor 4) belongs to the superfamily of G protein-coupled receptors (GPCRs). It is a 951 amino acid multi-pass membrane protein and has multiple N-terminal leucine-rich repeats, which are important for interaction with the glycoprotein ligands, and 7 transmembrane domains (1,3). LGR4 is highly expressed in the adult human pancreas but also with moderate levels of expression in placenta, kidney, brain and heart (2). LGR4 functions as an orphan receptor that may be involved in physiologic activities throughout the cell. It is overexpressed in various cancer types and is thought to enhance carcinoma invasiveness and metastasis, suggesting an important role in tumor progression.

UniProt: Q9BXB1