CD81 Antikörper

Produktnummer ABIN5541933

Der Ratte Monoklonal anti-CD81 Antikörper wird verwendet zum Nachweis von CD81 in Proben von Human. Er wurde validiert für FACS und EIA.

Kurzübersicht für CD81 Antikörper (ABIN5541933)

Target: CD81

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD81 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: QV-6A8-S3

Produktdetails anti-CD81 Antikörper

Spezifität: Recognizes Human CD81. Other species not tested. Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: cDNA encoding Human CD81

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 1.2 μg/10 6 cells. ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.2

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD81

Target: CD81

Andere Bezeichnung: cd81,tapa1

Hintergrund: CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL) (1). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins (2,3). CD81 is an essential HCV host factor as silencing of CD81 expression by CD81-specific monoclonal antibodies in hepatoma cells inhibits HCV entry (4).

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C