GNRH1 Antikörper (AA 11-60)

Produktnummer ABIN5541891

Der Kaninchen Polyklonal anti-GNRH1 Antikörper wird verwendet zum Nachweis von GNRH1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB und IHC (p).

Kurzübersicht für GNRH1 Antikörper (AA 11-60) (ABIN5541891)

Target: GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNRH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GNRH1 Antikörper

Bindungsspezifität: AA 11-60

Spezifität: This antibody detects endogenous levels of GnRH 1 protein.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Immunogen: Synthetic peptide corresponding to amino acids 11-60 of Human GnRH I.

Anwendungsinformationen

Applikationshinweise: Western blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 95 % by SDS-PAGE) Aff - Purified

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GNRH1

Target: GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))

Andere Bezeichnung: gnrh1,progonadoliberin-1

Hintergrund: GnRH is produced by hypothalamic neurons and secreted in a pulsatile manner into the capillary plexus of the median eminence. GnRH affects the release of lutenizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary. In addition to hypothalamic GnRH (GnRH I), a second GnRH form (GnRH II) functions primarily in the midbrain. GnRH is xpressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells. Unlike GnRH I, GnRH II is highly expressed outside the brain, particularly in the kidney, bone marrow and prostate, suggesting that it may have multiple functions. GnRH binds to a specific G protein-coupled receptor in the pituitary to regulate synthesis and secretion of gonadotropins.

UniProt: P01148

Pathways: Hormone Activity