GPR50 Antikörper

Produktnummer ABIN5541840

Der Maus Monoklonal anti-GPR50 Antikörper wird verwendet zum Nachweis von GPR50 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für GPR50 Antikörper (ABIN5541840)

Target: GPR50 (G Protein-Coupled Receptor 50 (GPR50))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GPR50 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1A3

Produktdetails anti-GPR50 Antikörper

Spezifität: This antibody detects Human GPR50.

Aufreinigung: Protein G

Immunogen: DNA vaccine

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections: 5 μg/mL. Positive control: Human placenta.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GPR50

Target: GPR50 (G Protein-Coupled Receptor 50 (GPR50))

Andere Bezeichnung: gpr50

Hintergrund: GPR50 or me latonin - related receptor is a 617 amino acid protein that belongs to the G - protein coupled receptor 1 family, containing one disulfide bond. GPR50 does not bind melatonin and its end ogenous ligand is still unknown. Nevertheless, this receptor has been shown to behave as an antagonist of the melatonin receptor MT 1. GPR50 has been identified as a genetic risk factor for bipolar disorder and major depression in women, and it has been linked to neurite outgrowth, lipid metabolism, stress response and energy homeostasis and torpor. Its expression seems to be limited to brain, particularly the hypothalamus and pituitary.

UniProt: Q13585