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GPR50 Antikörper

Der Maus Monoklonal Anti-GPR50-Antikörper wurde für IHC (p) validiert. Er ist geeignet, GPR50 in Proben von Human zu detektieren.
Produktnummer ABIN5541840

Kurzübersicht für GPR50 Antikörper (ABIN5541840)

Target

Alle GPR50 Antikörper anzeigen
GPR50 (G Protein-Coupled Receptor 50 (GPR50))

Reaktivität

  • 30
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 29
  • 2
Maus

Klonalität

  • 31
Monoklonal

Konjugat

  • 26
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GPR50 Antikörper ist unkonjugiert

Applikation

  • 21
  • 14
  • 12
  • 7
  • 6
  • 3
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

1A3
  • Spezifität

    This antibody detects Human GPR50.

    Aufreinigung

    Protein G

    Immunogen

    DNA vaccine

    Isotyp

    IgG1
  • Applikationshinweise

    Immunohistochemistry on paraffin sections: 5 μg/mL. Positive control: Human placenta.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    Haltbarkeit

    12 months
  • Target

    GPR50 (G Protein-Coupled Receptor 50 (GPR50))

    Andere Bezeichnung

    gpr50

    Hintergrund

    GPR50 or me latonin - related receptor is a 617 amino acid protein that belongs to the G - protein coupled receptor 1 family, containing one disulfide bond. GPR50 does not bind melatonin and its end ogenous ligand is still unknown. Nevertheless, this receptor has been shown to behave as an antagonist of the melatonin receptor MT 1. GPR50 has been identified as a genetic risk factor for bipolar disorder and major depression in women, and it has been linked to neurite outgrowth, lipid metabolism, stress response and energy homeostasis and torpor. Its expression seems to be limited to brain, particularly the hypothalamus and pituitary.

    UniProt

    Q13585
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