Rituximab Antikörper (HRP)
Kurzübersicht für Rituximab Antikörper (HRP) (ABIN5541687)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody specifically recognises the idiotypic determinants expressed by the Rituximab humanised monoclonal antibody. This antibody does not recognise other CD20 antibodies. It has been used to detect Rituximab bound to the surface of the Raji B cell line, however detection of Rituximab bound 'in vivo' to B-CLL cells has not been demonstrated. It is possible that complement deposition on Rituximab opsonised cells inhibits binding of the anti-Rituximab antibody to cell bound Rituximab (3). Clone MB2A4 has been used in ELISA assays to monitor the levels of rituximab in patient serum following therapy (4,5).
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Aufreinigung
- Affinity chromatography on Protein G
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Immunogen
- F(ab)2 fragment of Rituximab
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Isotyp
- IgG2a
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Applikationshinweise
- ELISA: 1/20000-1/20000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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Haltbarkeit
- 12 months
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- Rituximab
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Substanzklasse
- Antibody
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Hintergrund
- Rituximab is a therapeutic reagent directed against the human CD20 cell surface antigen.
Target
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