GLP1R Antikörper

Produktnummer ABIN5541471

Der Maus Monoklonal Anti-GLP1R Antikörper wurde für IHC (p) validiert. Er ist geeignet, GLP1R in Proben von Human zu detektieren.

Kurzübersicht für GLP1R Antikörper (ABIN5541471)

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GLP1R Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1H4

Produktdetails anti-GLP1R Antikörper

Spezifität: This antibody detects GLP-1R. The specificity of the antibody was verified by flow cytometry with cells expressing the recombinant protein. Aff. Const.: Human

Aufreinigung: Protein G

Immunogen: DNA vaccine

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections: 2 μg/mL (1/100) pretreatment with microwave required. Positive control: pancreas / adrenal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GLP1R

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Andere Bezeichnung: glp1 receptor

Hintergrund: Glucagon - like peptide 1 receptor belongs to the G - protein coupled receptor 2 family. The mature protein is made up of 440 amino acids with four disulfide bonds and three N - linked glycosylation sites. Glucagon - like peptide - 1 (GLP - 1) is a peptide hormone that functions as a messenger between various organs and tissues involved in glucose metabolism, and controls nutrient ingestion. Important sources for GLP - 1 include the intestine and brain stem and hypothalamus, while the receptor (GLP - 1R) is prominently expressed in pancreas, areas of the brain such as the hypothalamus, and peripheral nerves.

UniProt: P43220

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour