IKZF2 Antikörper (AA 51-107) (PE)

Produktnummer ABIN5541431

Dieser Hamster Monoklonal Antikörper detektiert spezifisch IKZF2 in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für IKZF2 Antikörper (AA 51-107) (PE) (ABIN5541431)

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Reaktivität: Human, Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser IKZF2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: 22F6

Produktdetails anti-IKZF2 Antikörper (PE)

Bindungsspezifität: AA 51-107

Spezifität: This antibody recognizes Helios, a transcription factor expressed in some hematopoietic stem cells, and at high levels in thymic-derived regulatory T cells.

Immunogen: Peptide coresponding to the amino acids 51-107 of Helios

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10 6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu IKZF2

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Andere Bezeichnung: znfn1a2 (ikzf2, helios)

Hintergrund: Helios, also known as IKZF2 (Ikaros family zinc finger protein 2) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Ikaros. Helios forms homo- and heterodimers with these proteins and is thought to function predominantly in early hematopoietic development. Expression of Helios, Aiolos and Ikaros is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Helios is expressed at early stages of thymocyte development. In mature T cells, Helios has been strongly associated with Treg cells.

UniProt: Q9UKS7