TIAM1 Antikörper

Produktnummer ABIN5541409

Dieses Anti-TIAM1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TIAM1 in WB und IHC (fro). Geeignet für Human.

Kurzübersicht für TIAM1 Antikörper (ABIN5541409)

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TIAM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: F5S F6-2

Produktdetails anti-TIAM1 Antikörper

Spezifität: This antibody clone F5S F6.2 is directed against the N-terminal region of Tiam1.

Aufreinigung: Purified

Immunogen: T-cell lymphoma invasion and metastasis-inducing protein 1 (Tiam1).

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Western Blot. Immunohistochemistry on Frozen Sections.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu TIAM1

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Andere Bezeichnung: tiam1

Hintergrund: Tiam1, also known as T-cell lymphoma invasion and metastasis-inducing protein 1, is a protein that in humans is encoded by the TIAM1 gene. TIAM1 is tightly associate with BAIAP2 as a subunit. It contains one DH (DBL-homology) domain, one PDZ domain, two PH domains and one Ras-binding RBD domain. TIAM1 modulates the activity of Rho GTP-binding proteins and connects extracellular signals to cytoskeletal activities. In addition, TIAM1 activates Rac1, CDC42, and to a lesser extent RhoA. TIAM1 is found in virtually all tumor cell lines examined including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.

UniProt: Q13009