MHC Class I (Monomorphic) Antikörper (PE)

Produktnummer ABIN5541362

Produktdetails

Target: MHC Class I (Monomorphic)

Reaktivität: Pferd

Wirt: Maus

Klonalität: Monoklonal

Konjugat: PE

Applikation: Flow Cytometry (FACS)

Spezifität: All tissues Species: Equine (Horse).

Aufreinigung: Affinity chromatography on Protein A

Immunogen: Equine leucocytes

Klon: CVS22

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Neat, use 10 μL to label 10e6 cells in 100 μL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Antigendetails

Target: MHC Class I (Monomorphic)

Hintergrund: MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.