PAK6 Antikörper (pSer560, pSer602)

Produktnummer ABIN5541295

Dieses Anti-PAK6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PAK6 in WB. Geeignet für Human und Maus.

Kurzübersicht für PAK6 Antikörper (pSer560, pSer602) (ABIN5541295)

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PAK6 Antikörper

Bindungsspezifität: pSer560, pSer602

Spezifität: The antibody detects endogenous levels of PAK5/6 only when phosphorylated at serine 602/560.

Aufreinigung: Affinity chromatography using epitope-specific peptide

Immunogen: Peptide sequence around phosphorylation site of Serine 602/560(R-K-S(p)-L-V) derived from Human PAK5/6 (KLH-conjugated)

Anwendungsinformationen

Applikationshinweise: Western blot: 1:500~1:1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu PAK6

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Andere Bezeichnung: pak6

Hintergrund: This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development.

UniProt: Q9NQU5