CEACAM5 Antikörper

Produktnummer ABIN5541179

Produktdetails anti-CEACAM5 Antikörper

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM5 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunocytochemistry (ICC)

Spezifität: This antibody recognizes exclusively CECAM5.

Aufreinigung: Protein G Chromatography

Immunogen: Extracted protein of CEACAM5. Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells

Klon: 26-3-13

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200. Flow Cytometry: 1.2 μg/10 6 cells. Immunofluorescence: 1/200. Western blot: 4 μg/mL. Immunohistochemistry on Cryo -Sections: 1-2 μg/10

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.2 without preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Referenzen für anti-CEACAM5 Antikörper (ABIN5541179)

Schmitter, Agerer, Peterson, Munzner, Hauck: "Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens." in: The Journal of experimental medicine, Vol. 199, Issue 1, pp. 35-46, (2004) (PubMed).

Details zu CEACAM5

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Andere Bezeichnung: cd66e,ceacam5 (CEACAM5 Produkte)

Synonyme: CD66e antikoerper, CEA antikoerper, CEACAM5 antikoerper, CEACAM antikoerper, 1600029H12Rik antikoerper, Psg30 antikoerper, carcinoembryonic antigen related cell adhesion molecule 5 antikoerper, carcinoembryonic antigen antikoerper, carcinoembryonic antigen-related cell adhesion molecule 5 antikoerper, carcinoembryonic antigen-related cell adhesion molecule 8 antikoerper, carcinoembryonic antigen gene family antikoerper, CEACAM5 antikoerper, Ceacam5 antikoerper, LOC100409241 antikoerper, Cea antikoerper

Hintergrund: CEACAM5 (CEA-related cell adhesion molecule 5, CEA) belongs to the carcinoembryonic antigen (CEA) gene family (1,2). It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein with a Mr of 180,000-200,000 which is most strongly expressed on epithelial cells of the fetal and adult colon and to a minor extent on epithelial cells of the stomach and sweat glands, squamous epithelial cell of the tongue, esophagus and cervix. CEACAM5 is used as a tumor marker for early detection of recurrent disease due to its expression in adenocarcinomas of the colon, lung, breast, stomach and pancreas and in mucinous ovarian carcinomas (3). Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3).

UniProt: P06731