CEACAM8 Antikörper

Produktnummer ABIN5541174

Der Maus Monoklonal anti-CEACAM8 Antikörper wird verwendet zum Nachweis von CEACAM8 in Proben von Human. Er wurde validiert für FACS und EIA.

Kurzübersicht für CEACAM8 Antikörper (ABIN5541174)

Target: CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM8 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: GM2H6

Produktdetails anti-CEACAM8 Antikörper

Spezifität: Recognizes CEACAM8 (CD66b/NCA-95).

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Genetic immunisation with cDNA encoding Human CEACAM8.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. Flow cytometry: 1.2 μg/10 6 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2 without preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CEACAM8

Target: CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

Andere Bezeichnung: cd66b,ceacam8

Hintergrund: CEA-related cell adhesion molecule 8 (CEACAM8, CD66b) belongs to the carcinoembryonic antigen (CEA) gene family (1,3,4). It encodes a glycosylphosphatidylinositol (GPI)-linked glycoprotein with a Mr of 95,000 which is expressed in cells of the granulocyte-lineage. It is expressed in neutrophils and eosinophils and is characterized as a granulocyte-specific activation antigen. CEACAM8 could serve as a marker for granulocyte activities (2). Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A and B do-mains.

UniProt: P31997