ASF1B Antikörper (AA 1-202)

Produktnummer ABIN5541030

Der Maus Monoklonal Anti-ASF1B-Antikörper wurde für WB und EIA validiert. Er ist geeignet, ASF1B in Proben von Human zu detektieren.

Kurzübersicht für ASF1B Antikörper (AA 1-202) (ABIN5541030)

Target: ASF1B (ASF1 Anti-Silencing Function 1 Homolog B (ASF1B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ASF1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT1D4

Produktdetails anti-ASF1B Antikörper

Bindungsspezifität: AA 1-202

Spezifität: Recognizes Human ASF1B. Other species not tested.

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human ASF1B (1-202aa) purified from E. coli.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu ASF1B

Target: ASF1B (ASF1 Anti-Silencing Function 1 Homolog B (ASF1B))

Andere Bezeichnung: asf1b

Hintergrund: ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. Delivering histone H3/H4 dimers to CAF-1 or HIRA histone deposition complexes to facilitate replication-coupled and replication-independent nucleosome assembly on DNA. Both ASF1A and ASF1B are phosphorylated in S phase by the Tousled-like kinases TLK1 and TLK2, and are dephosphorylated when TLK1 and TLK2 are inactivated by Chk1 kinase in response to replicative stress.

UniProt: Q9NVP2

Pathways: Regulation of Cell Size