NCR1 Antikörper (Biotin)

Produktnummer ABIN5540952

Der Ratte Monoklonal anti-NCR1 Antikörper wird verwendet zum Nachweis von NCR1 in Proben von Maus. Er wurde validiert für FACS.

Kurzübersicht für NCR1 Antikörper (Biotin) (ABIN5540952)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser NCR1 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: 29A1-4

Produktdetails anti-NCR1 Antikörper (Biotin)

Spezifität: This antibody (clone 29A1.4) recognizes natural killer cell p46 related protein (NKp46) also known as CD335. Staining is not strain specific and the antibody has been used to stain C57BL/6, SJL, CBA/CA and BALB/c Mouse strains. Clone 29A1.4 also activates NK cells in vitro. It does not deplete NK cells in vivo. Species: Mouse.

Immunogen: NKP46-IgG1 Fc fusion protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Use 10 μL of 1/5-1/10 diluted antibody to label 10 6 cells in 100 μL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Andere Bezeichnung: cd335,nkp46

Hintergrund: CD335 is uniquely expressed by resting and activated natural killer (NK) cells, but no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes. It is a major NK cell lysis receptor for autologous pathogen-infected and tumor target cells during natural cytotoxicity responses. Ligands of CD335 include viral hemagglutinins (HAs) and heparan sulfate proteoglycans (HSPGs) on the surface of tumor cells.

UniProt: Q8C567

Pathways: Regulation of Leukocyte Mediated Immunity