This antobody recognizes CD157, an approximately 45 kDa GPI-anchored protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells.
Aufreinigung
Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Flow cytometry. Immunoprecipitation. Western blot: non-reducing conditions. Immunohistochemistry (frozen sections).
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
BST1
(Bone Marrow Stromal Cell Antigen 1 (BST1))
Andere Bezeichnung
cd157,bst1
Hintergrund
CD157 (cADPr hydrolase 2) is a GPI-anchored ectoenzyme possessing ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activity. It uses NAD and cADP-ribose as substrates. CD157 is expressed on granulocytes, monocytes, macrophages, follicular dendritic cells, bone marrow stromal cells and human umbilical cord vein endothelial cells. In case of rheumatoid arthritis is expression is often higher and it is also differentially expressed in the myeloid leukemias. It may also have a signaling role.