Der Maus Monoklonal anti-ITGA6 Antikörper (Klon Mab-5A) (ABIN5540896) detektiert spezifisch ITGA6 in FACS, IHC (fro) und EIA.
Dieser Antikörper reagiert spezifisch mit Proben aus Ratte.
This CD49f antibody, clone Mab-5A recognizes Rat CD49f, also known as Integrin alpha-6, VLA-6 or CD49 antigen-like family member F. CD49f is a 1130 amino acid ~130 kDa single pass type 1 transmembrane glycoprotein which functions as a receptor for laminin when in association with either beta-1 or beta-4 integrins on platelets and epithelial cells respectively. Clone Mab-5A does not react with Rat fibroblasts. Species: Rat.
Aufreinigung
Affinity Chromatography on Protein G
Immunogen
Rat oesophageal carcinoma cell line B2T. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
ITGA6
Reaktivität: Ratte
FACS
Wirt: Maus
Monoclonal
Mab-5A
PE
Applikationshinweise
ELISA. Flow Cytometry. Immunohistochemistry on Frozen Sections.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS Preservatives: 0.09 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
ITGA6
(Integrin, alpha 6 (ITGA6))
Andere Bezeichnung
cd49f,itga6
Hintergrund
CD49f is a 120 kD integrin family member, also known as VLA-6 alpha chain and alpha6 integrin subunit. CD49f associates with either integrin beta1 (CD29) or integrin beta4 (CD104) to form receptors (VLA-6 or alpha6 beta4 complex) for laminin and kalinin. CD49f is expressed on platelets, monocytes, T cells, placental trophoblasts, epithelial and endothelial cells. CD49f is involved in adhesion and can act as a co-stimulatory molecule for T cell activation and proliferation.