ITGA6 Antikörper
Kurzübersicht für ITGA6 Antikörper (ABIN5540896)
Target
Alle ITGA6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This CD49f antibody, clone Mab-5A recognizes Rat CD49f, also known as Integrin alpha-6, VLA-6 or CD49 antigen-like family member F. CD49f is a 1130 amino acid ~130 kDa single pass type 1 transmembrane glycoprotein which functions as a receptor for laminin when in association with either beta-1 or beta-4 integrins on platelets and epithelial cells respectively. Clone Mab-5A does not react with Rat fibroblasts. Species: Rat.
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Aufreinigung
- Affinity Chromatography on Protein G
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Immunogen
- Rat oesophageal carcinoma cell line B2T. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA. Flow Cytometry. Immunohistochemistry on Frozen Sections.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS Preservatives: 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Haltbarkeit
- 12 months
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- ITGA6 (Integrin, alpha 6 (ITGA6))
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Andere Bezeichnung
- cd49f,itga6
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Hintergrund
- CD49f is a 120 kD integrin family member, also known as VLA-6 alpha chain and alpha6 integrin subunit. CD49f associates with either integrin beta1 (CD29) or integrin beta4 (CD104) to form receptors (VLA-6 or alpha6 beta4 complex) for laminin and kalinin. CD49f is expressed on platelets, monocytes, T cells, placental trophoblasts, epithelial and endothelial cells. CD49f is involved in adhesion and can act as a co-stimulatory molecule for T cell activation and proliferation.
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UniProt
- P23229
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Pathways
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
Target
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