MRGPRX2 Antikörper

Produktnummer ABIN5540874

Der Maus Monoklonal anti-MRGPRX2 Antikörper wird verwendet zum Nachweis von MRGPRX2 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für MRGPRX2 Antikörper (ABIN5540874)

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MRGPRX2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1D3

Produktdetails anti-MRGPRX2 Antikörper

Spezifität: This antibody detects Human MRGPRX2 (GPCRx11).

Aufreinigung: Protein G

Immunogen: DNA vaccine

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections: 1 μg/mL (1/200). Positive control: Human placenta.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu MRGPRX2

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Andere Bezeichnung: mrgprx2

Hintergrund: MRGPRX2 or cortistatin receptor is a 330 amino acid protein that belongs to the G - protein coupled receptor 1 family. Mas - related G - protein - coupled receptors (Mrgprs) represent a large family of orphan receptors specifically expressed in small - diameter nociceptive primary sensory neurons. Physiological functions include mediation of itch or regulat ion of persistent pathological pain. Cortistatin - 14, which is involved in sleep regulation, locomotor activity, and cortical function, seems to be a high potency ligand at this receptor. Also, the multifunctional antibacterial protein LL - 37 has been shown to activate cells presumably through MRGPRX2.

UniProt: Q96LB1