CCR2 Antikörper

Produktnummer ABIN5540857

Dieser Anti-CCR2 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von CCR2 in IHC (p). Geeignet für Human.

Kurzübersicht für CCR2 Antikörper (ABIN5540857)

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCR2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 7A7

Produktdetails anti-CCR2 Antikörper

Spezifität: This antibody detects

Aufreinigung: Protein G

Immunogen: DNA vaccine

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections: 4-8-μg/mL (1/50-1/100) Pretreatment with proteinase K required.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CCR2

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Andere Bezeichnung: cd192,ccr2

Hintergrund: CCR2B is a 374 amino acid protein that belongs to the G - protein coupled receptor 1 family with seven transmembrane domains. It mediates the chemotactic properties of monocyte chemoattractant protein 1 (MCP - 1) which is secreted by endothelial and epithelial cells, vascular smooth muscle and hematopoietic cells. MCP - 1 is a potent chemoattractant for monocytes and lymphocytes. It is responsible for monocyte infiltration in a variety of chronic inflammatory diseases.

UniProt: P41597

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process