HINT2 Antikörper (AA 18-163)

Produktnummer ABIN5540727

Der Maus Monoklonal Anti-HINT2-Antikörper wurde für WB, FACS und EIA validiert. Er ist geeignet, HINT2 in Proben von Human zu detektieren.

Kurzübersicht für HINT2 Antikörper (AA 18-163) (ABIN5540727)

Target: HINT2 (Histidine Triad Nucleotide Binding Protein 2 (HINT2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HINT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: AT5B10

Produktdetails anti-HINT2 Antikörper

Bindungsspezifität: AA 18-163

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human HINT2 (18-163aa) purified from E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu HINT2

Target: HINT2 (Histidine Triad Nucleotide Binding Protein 2 (HINT2))

Andere Bezeichnung: hint2

Hintergrund: Histidine triad nucleotide binding protein 2 (HINT2) is a mitochondrial protein. This protein is an AMP-lysine hydrolase and phosphoamidase and may contribute to tumor suppression. This protein is a member of the HIT superfamily and Hint subfamily, which are characterized as nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides. HINT2 regulates steroidogenesis through calcium-dependent and calcium-independent siglling pathways that may serve to maintain a favorable mitochondrial potential. Its role in calcium homeostasis may also contribute to its proapoptotic function in hepatocytes and other non-steroidogenic cells, though the exact mechanism remains unclear.

UniProt: Q9BX68