KCNIP1 Antikörper (AA 12-22)

Produktnummer ABIN5540452

Dieses Anti-KCNIP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KCNIP1 in WB und EIA. Geeignet für Maus.

Kurzübersicht für KCNIP1 Antikörper (AA 12-22) (ABIN5540452)

Target: KCNIP1 (Kv Channel Interacting Protein 1 (KCNIP1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-KCNIP1 Antikörper

Bindungsspezifität: AA 12-22

Sequenz: QTKQRRPSKD K

Spezifität: This antibody is reactive to the 27 kDa Kchip1 in Mouse and other species with consensus Kchip1 sequence.

Aufreinigung: Protein G affinity

Immunogen: A synthetic peptide derived from the amino sequence amino acid 12-22 of mouse Kchip1, conjugated with KLH

Anwendungsinformationen

Applikationshinweise: ELISA: Dilute the antibody approx. 1:300,000 for detection of Kchip1 peptide (QTKQRRPSKDK) coated on ELISA plate. Western blot: Dilute approx. 1:4,000 to detect the 27 kDa Kchip1 in mouse brain extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.01M PBS, pH 7.4

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu KCNIP1

Target: KCNIP1 (Kv Channel Interacting Protein 1 (KCNIP1))

Andere Bezeichnung: kcnip1,vabp

Hintergrund: KChIP1 is an important member of the potassium channel interacting protein family. It binds to and influences the voltage gated potassium (Kv) channel. Like all other members in the family, KChIP1 has calcium binding domains (EF-hand-like) that sense calcium concentrations to regulate Kv channel. KChIP1 frequently forms complex with the rapid inactivating A-type Kv channels. It may play a role in modulating somatodendritic excitability, and the repolarization of cardiac myocytes following action potential. It is also reported that KChIP1 is associated with the GABAergic synapses in hippocampus.