GARS Antikörper (AA 43-289)

Produktnummer ABIN5540351

Dieser Maus Monoklonal Antikörper detektiert spezifisch GARS in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GARS Antikörper (AA 43-289) (ABIN5540351)

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GARS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT4E10

Produktdetails anti-GARS Antikörper

Bindungsspezifität: AA 43-289

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human GARS (43-289aa) purified from E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GARS

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Andere Bezeichnung: glycyl-trna synthetase

Hintergrund: GARS, also known as glycyl-tRNA synthetase, is one of the aminoacyl-tRNA synthetase that charge tRNAs with their cognate amino acids. Defects in the gene encoding GlyRS is the cause of Charcot-Marie-Tooth disease type 2D (CMT2D), which is an autosomal dominant inherited disease characterized by severe weakness, atrophy and absence of deep tendon reflexes in the upper extremities. Defects in the GlyRS gene is also the cause of distal hereditary muscular neuropathy type V (HMN5), a disease similar to CMT2D, though the distal sensory involvement is less severe in HMN5 patients.

UniProt: P41250

Pathways: Ribonucleoside Biosynthetic Process