Cytokeratin 1 Antikörper (pan) (FITC)

Produktnummer ABIN5540281

Dieses Anti-Cytokeratin 1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Cytokeratin 1 in FACS, ICC und IF. Geeignet für Human, Ratte, Maus, Rind (Kuh), Kaninchen, Huhn, Affe und Schwein.

Kurzübersicht für Cytokeratin 1 Antikörper (pan) (FITC) (ABIN5540281)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Huhn, Affe, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 1 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: AE1-AE3

Produktdetails anti-Cytokeratin 1 Antikörper (FITC)

Bindungsspezifität: pan

Spezifität: AE 1/AE3 represents an excellent marker for distinguishing carcinomas from non-epithelial tumors reacts with all epithelium-derived tumors and their neoplasms. Decorates the majority of type I and type II keratins (formerly also designated cytokeratins). This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas. This antibody AE 1/AE 3 recognizes Low Molecular Weight Cytokeratins (CK 10 (56.5), CK14 (50), CK15 (50), CK16 (48) and CK19 (40) of the acidic family and CK1 (67), CK2 (65.5), CK3 (64), CK4 (59), CK5 (58) CK6 (56) and CK8 (52.5).

Aufreinigung: Protein A Chromatography

Immunogen: Human epidermal keratin.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 10-20 μg /mL (1/10-1/20), incubate for 2 hours in the dark at RT or it can also be incubated overnight at 4 °C. Flow Cytometry: 0.2-1.0 μg/0.1 mL (1/200-1/1,000) (Not tested in our lab).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch.

Details zu Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Andere Bezeichnung: cytokeratin

Hintergrund: Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1(67), CK2(65.5), CK3(64), CK4(59), CK5(58), CK6(56), CK7(54), CK8(52.5) and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10 (56.5), CK12 (56), CK13 (53), CK14 (50), CK16 (48), CK17 (46), CK18 (45), CK19 (48) and CK20 (46).