CACYBP Antikörper (AA 1-185)

Produktnummer ABIN5540232

Der Maus Monoklonal anti-CACYBP Antikörper wird verwendet zum Nachweis von CACYBP in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für CACYBP Antikörper (AA 1-185) (ABIN5540232)

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CACYBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT3G8

Produktdetails anti-CACYBP Antikörper

Bindungsspezifität: AA 1-185

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human CACYBP (1-185aa) purified from E. coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CACYBP

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Andere Bezeichnung: cacybp

Hintergrund: CACYBP (Calcyclin-binding protein) is primarily a nuclear protein that contains one CS domain and one SGS domain. CACYBP is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in ubiquitin E3 complexes. It also participates in the ubiquitin-mediated degradation of b-catenin. CACYBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on b-catenin protein expression and transcriptional activation of TCF/LEF.

UniProt: Q9HB71

Pathways: Response to Growth Hormone Stimulus