CX3CR1 Antikörper

Produktnummer ABIN5540227

Dieses Anti-CX3CR1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CX3CR1 in IHC (p). Geeignet für Human.

Kurzübersicht für CX3CR1 Antikörper (ABIN5540227)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CX3CR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1G4

Produktdetails anti-CX3CR1 Antikörper

Spezifität: This antibody detetcs CX3C Receptor 1. The specificity of the antibody was verified by flow cytometry with cells expressing the recombinant protein. The epitope has not been further characterized.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: DNA vaccine

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections: 2 μg/mL (1/100), pretreatment with proteinase K required. Suggested Positive Control: Human brain cortex.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL BSA

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Andere Bezeichnung: cx3cr1,gpr13

Hintergrund: G-protein coupled receptor 1 3 (GPR13) is a 355 amino acid protein that belongs to the G - protein coupled receptor 1 family. Biologically, the fractalkine (CX3CL1) to fractalkine receptor (CX3CR1) interactions play an important role in macrophage recruitment to target organs such as the brain, the intestine, the liver or the lungs. Accordingly, expression of the CX3CR1 has been described in inflammation - and tumor - associated macrophages, intestinal lamina propia macrophages, and B cells. Also, CX3CR1 mediates adhesive and migratory functions and acts as a coreceptor with CD4 for HIV - 1 virus gp160 envelope protein.

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin