Integrin beta 3 Antikörper (APC)

Produktnummer ABIN5540114

Dieser Maus Monoklonal Antikörper detektiert spezifisch Integrin beta 3 in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Primate.

Kurzübersicht für Integrin beta 3 Antikörper (APC) (ABIN5540114)

Target: Integrin beta 3 (ITGB3)

Reaktivität: Human, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 3 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: VIPL2

Produktdetails anti-Integrin beta 3 Antikörper (APC)

Spezifität: This antibody recognizes CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10 6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: PStore the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Andere Bezeichnung: cd61,itgb3

Hintergrund: CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex