Thrombomodulin Antikörper
Kurzübersicht für Thrombomodulin Antikörper (ABIN5540104)
Target
Alle Thrombomodulin (THBD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Spezifität
- Recognises Thrombomodulin (TM), a 105 kDa protein.
-
Aufreinigung
- Ion Exchange Chromatography
-
Immunogen
- Eahy 926 cell lines.
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
- ELISA.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- 0.22 μm Sterile-filtered PBS. Carrier and preservative free.
-
Konservierungsmittel
- Azide free
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
-
Haltbarkeit
- 12 months
-
-
- Thrombomodulin (THBD)
-
Andere Bezeichnung
- cd141,thbd
-
Hintergrund
- CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.
-
UniProt
- P07204
Target
-