Der Maus Monoklonal anti-Thrombomodulin Antikörper (Klon B-S24) (ABIN5540104) detektiert spezifisch Thrombomodulin in EIA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
0.22 μm Sterile-filtered PBS. Carrier and preservative free.
Konservierungsmittel
Azide free
Lagerung
4 °C
Informationen zur Lagerung
Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
Thrombomodulin (THBD)
Andere Bezeichnung
cd141,thbd
Hintergrund
CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.