CBR1 Antikörper (AA 1-277)

Produktnummer ABIN5540084

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CBR1 in WB, ICC, IF, FACS und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CBR1 Antikörper (AA 1-277) (ABIN5540084)

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: AT2D6

Produktdetails anti-CBR1 Antikörper

Bindungsspezifität: AA 1-277

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human CBR1 (1-277aa) purified from E. coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Andere Bezeichnung: carbonyl reductase 1

Hintergrund: Carbonyl reductase 1 (CBR1) is a DPH-dependent, monomeric, and cytosolic enzyme belonging to a family of short-chain dehydrogeses/reductases. This protein consists of 277 amino acid residues and is widely distributed in human tissues such as liver, epidermis, stomach, small intestine, kidney, neurol cells, and smooth muscle fiber. CBR1 metabolizes many toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E).

UniProt: P16152