GAP43 Antikörper (C-Term)

Produktnummer ABIN5540032

Der Huhn Polyklonal anti-GAP43 Antikörper (ABIN5540032) detektiert spezifisch GAP43 in WB, IF und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für GAP43 Antikörper (C-Term) (ABIN5540032)

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Reaktivität: Human, Ratte, Maus

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser GAP43 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-GAP43 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects GAP43.

Aufreinigung: Ig Fraction

Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region of the rat GAP43 sequence

Anwendungsinformationen

Applikationshinweise: Western blot: 1/2000. Immunoflourescence: 1/500.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 10 mM Sodium azide

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GAP43

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Andere Bezeichnung: gap43

Hintergrund: GAP-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration (Benowitz and Routtenberg, 1997). There is also evidence from knockout animals that GAP-43 serves to amplify pathfinding signals from the growth cone (Strittmatter et al., 1995). GAP-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser 41 by protein kinase C modulates the interaction of GAP-43 with actin (He et al., 1997) and may also affect neurotransmitter release during forms of plasticity like LTP (Hulo et al., 2002).

UniProt: P07936