ACTC1 Antikörper (N-Term)

Produktnummer ABIN5539979

Dieses Maus Monoklonal-Antikörper erkennt spezifisch ACTC1 in WB, IHC (fro) und EIA. Er zeigt eine Reaktivität gegenüber Human, Ratte, Zebrafisch (Danio rerio), Kaninchen und Schwein.

Kurzübersicht für ACTC1 Antikörper (N-Term) (ABIN5539979)

Target: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Reaktivität: Human, Ratte, Zebrafisch (Danio rerio), Kaninchen, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ACTC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: 22D3

Produktdetails anti-ACTC1 Antikörper

Bindungsspezifität: N-Term

Sequenz: Ac-DDEETTALVC -COOH

Spezifität: This 22D3 Monoclonal antibody is highly specific for Alpha-Cardiac Actin, and does not cross react with other Actin isoforms.

Aufreinigung: Purified

Immunogen: Peptide comprising the N-terminal nonapeptide of alpha-Cardiac Actin with an acetylated N-terminus coupled to keyhole limpet hemocyanin through the cysteine residue.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Flow Cytometry. Immunoblotting. Immunofluorescence. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin-Embedded Sections. Recommended Dilutions : 1/100-1/1000 for Immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent and 1/1000-1/5000 for immunoblotting applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freeze-thaw cycles. Shelf life: One year from despatch.

Details zu ACTC1

Target: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Andere Bezeichnung: alpha 1 cardiac muscle actin,actc1

Hintergrund: Among the six actin isoforms described in mammals, two are found in virtually all cells (β- and γ-cytoplasmic), two are detected in smooth muscle cells (α- and γ-smooth muscle) and two are present in striated muscles, one predominantly in skeletal (α-skeletal) and one in cardiac (α-cardiac) muscle cells. These actin isoforms differ slightly in their N-terminus, but the sequence of each of these actins is highly conserved in higher vertebrates. Cardiac α-actin, which is the main actin isoform in the adult heart, has also been shown to be the predominant form in early muscle development. In later development the expression of α-cardiac actin is down regulated and α-skeletal actin becomes the dominant isoform in the adult skeletal muscle.

Pathways: Myometrial Relaxation and Contraction