ACPP Antikörper

Produktnummer ABIN5539951

Dieses Anti-ACPP-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ACPP in FACS, EIA und ELISA (Detection). Geeignet für Human.

Kurzübersicht für ACPP Antikörper (ABIN5539951)

Target: ACPP (Acid Phosphatase, Prostate (ACPP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ACPP Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Enzyme Immunoassay (EIA), ELISA (Detection)

Klon: LT-3D1

Produktdetails anti-ACPP Antikörper

Spezifität: Recognizes Prostatic Acid Phosphatase PAP (PAcP, ACPP).

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Genetic immunisation with cDNA encoding Human PAP.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1.2 μg/10e6 cells. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. ELISA (detection): With clone LT-6C11-A1 as capture antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu ACPP

Target: ACPP (Acid Phosphatase, Prostate (ACPP))

Andere Bezeichnung: acpp,prostatic acid phosphatase

Hintergrund: Human prostatic acid phosphatase (PAP) is a non-specific phosphomonoesterase, synthesised and secreted into seminal plasma under androgenic control. Human PAP is a 100 kDa glycoprotein containing two subunits of approximately 50 kDa each (1,2). It catalyses the dephosphorylation of organic monophosphate esters, demonstrating optimum activity at an acid pH . Produced by the prostatic epithelium, serum levels of PAP are very low in healthy individuals, but are often elevated in malignant and benign prostatic disease while it has been used as a marker of diagnosis and therapy control of cancer of the prostate gland (3).

UniProt: P15309

Pathways: Synaptic Membrane, Ribonucleoside Biosynthetic Process