DIAPH3 Antikörper (C-Term)

Produktnummer ABIN5539348

Produktdetails anti-DIAPH3 Antikörper

Target: DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

Bindungsspezifität: AA 1061-1090, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DIAPH3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DIAPH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1090 amino acids from the C-terminal region of human DIAPH3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DIAPH3

Target: DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

Andere Bezeichnung: DIAPH3 (DIAPH3 Produkte)

Synonyme: Diap3 antikoerper, DIAP3 antikoerper, DIAPH3 antikoerper, 4930417P13Rik antikoerper, Dia2 antikoerper, Diaph3 antikoerper, Drf3 antikoerper, mDia2 antikoerper, mKIAA4117 antikoerper, p134MDia2 antikoerper, AN antikoerper, AUNA1 antikoerper, DIA2 antikoerper, DRF3 antikoerper, NSDAN antikoerper, diap3 antikoerper, diaphanous-related formin 3 antikoerper, diaphanous related formin 3 antikoerper, diaphanous homolog 3 (Drosophila) antikoerper, Diaph3 antikoerper, DIAPH3 antikoerper

Hintergrund: DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).

Molekulargewicht: 137 kDa

Gen-ID: 81624

UniProt: Q9NSV4