SFTPB Antikörper (AA 129-158)

Produktnummer ABIN5537428

Produktdetails anti-SFTPB Antikörper

Target: SFTPB (Surfactant Protein B (SFTPB))

Bindungsspezifität: AA 129-158

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFTPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SFTPB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-158 amino acids from the Central region of human SFTPB.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SFTPB

Target: SFTPB (Surfactant Protein B (SFTPB))

Andere Bezeichnung: SFTPB (SFTPB Produkte)

Synonyme: PSP-B antikoerper, SFTB3 antikoerper, SFTP3 antikoerper, SMDP1 antikoerper, SP-B antikoerper, AI562151 antikoerper, SF-B antikoerper, Sftp-3 antikoerper, Sftp3 antikoerper, Sp-b antikoerper, SFTPB antikoerper, sftpb antikoerper, xSP-B antikoerper, surfactant protein B antikoerper, surfactant associated protein B antikoerper, surfactant, pulmonary-associated protein B L homeolog antikoerper, SFTPB antikoerper, Sftpb antikoerper, sftpb.L antikoerper

Hintergrund: SFTPB is the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.

Molekulargewicht: 42 kDa

Gen-ID: 6439

UniProt: P07988